Glycine zwitterion test
URL:
?state=neutral (H on COOH) ·
?state=zwitterion (H on NH3+)
Neutral glycine H
2N-CH
2-COOH in a water shell. Real water stabilizes the
zwitterion +H
3N-CH
2-COO
− by ~10 kcal/mol.
Watch the H of COOH — does it transfer to NH
2 (intramolecular) or through water
(Grotthuss-like)?